Insufficient trophic support causes progressive neurodegeneration
In the short term, insufficient B12 levels can lead to deep fatigue, mood changes, and dementia-like qualities, preventing you from feeling your best and performing at your highest energy level
This was documented in a landmark 1982 New England Journal of Medicine report that identified benzyl alcohol doses exceeding 99 mg/kg/day as toxic in low-birth-weight neonates (PMID: 7133084)
The mechanism likely involves stress reduction (lowering cortisol that suppresses BDNF) combined with attentional training that directly engages BDNF-dependent hippocampal and prefrontal circuits
Research over the past two decades has shown that microbiome composition can influence: Energy extraction from food Fat storage signaling Immune activity Hormone production related to appetite Some microbial populations are associated with increased energy harvest from dietary carbohydrates, which may contribute to weight gain in certain individuals
Potential Benefits (Reported in Literature) May support cellular energy production and mitochondrial function through replenishment of NAD+ pools [1] [8]
