Cardiovasc Res (2011) 92(3):4018
In the retinal ischemia/reperfusion injury mouse model, retinal ganglion cells, photoreceptor cells, and pigment epithelial cells exhibited mitochondrial shrinkage, along with iron accumulation, increased reactive oxygen species, elevated MDA levels, and reduced GSH levels, leading to significant visual function damage
GHK-Cu no est incluido en la lista de sustancias prohibidas de la WADA ni de otras agencias antidopaje principales
Interventions targeting support for antioxidant defenses, iron homeostasis modulation, or prevention of lipid peroxidation have been shown to attenuate trophoblast dysfunctions caused by ferroptosis
Acknowledgements We thank CHA Bio Complex for excellent guidance and assistance with the performed mouse experiments
Sayin VI, Ibrahim MX, Larsson E, Nilsson JA, Lindahl P, Bergo MO