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Unlike earlier compounds that affected multiple methyltransferases, 5-amino-1MQ demonstrates remarkable specificity for NNMT without inhibiting related SAM-dependent enzymes or components of the NAD+ salvage pathway

Patients interested in peptide treatments should only pursue them under the direct supervision of qualified medical experts

Subsequent work by Heffernan and coworkers (2001) confirmed the peptides effects in obese mouse models, with chronic administration associated with reduced body weight gain and decreased adiposity without concurrent changes in food intake

The legal and health risks of obtaining these compounds through grey-market channels are therefore considerable