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Start: 100 mcg nightly

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The result can include: Reduced receptor binding Lower biological activity Molecular fragmentation Loss of analytical purity Oxidation is accelerated by: Light Heat Air exposure Metal contamination Deamidation Certain amino acid sequences undergo spontaneous deamidation after reconstitution

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Summary of the 2023 report of the international consultation on incontinence interstitial cystitis/bladder pain syndrome (IC/BPS) committee