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In some instances, local administration to the ear provides a higher therapeutic index for an active agent that otherwise have dose-limiting systemic toxicity

likely a result of the small sample size (n=6/group) in this pilot study

In most diseases, ROS appear to have a direct connection with inflammaging and cell senescence, and oxidative stress and inflammaging increase the aging-related phenotype, and induce and aggravate the inflammatory response, creating a chronic state of systemic inflammation (290297)

The life saving effect of pentadecapeptide BPC

The brain and gut communicate constantly through the vagus nerve, meaning gastrointestinal discomfort during opiate withdrawal can further intensify anxiety and emotional distress through bidirectional neural signaling

Its not always easy to parse which of the many biohacks Asprey touts are scammy or overstated, which are plain old common sense, and which are poised to become the hot new thing