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Funding: The work was supported by the Spanish Ministry of Science and Innovation, grant number BFU2005/230 and CIBERER and grant form Generalitat Valenciana number AP-004/07

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BPC-157, by contrast, operates largely through modulation of the nitric oxide (NO) system and upregulation of growth factor expression, including VEGF and EGF, supporting angiogenesis and granulation tissue formation