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In this study, we demonstrated that the treatment with the neuropeptide cortistatin alleviates chronic neuropathic pain in a variety of well-established preclinical models of chronic constriction and transection of the sciatic nerve and of diabetic peripheral neuropathy

and they may boost your gut health (13)

Baines, C

For example, one study documented persistent alterations in more than 800 phosphosites in hepatocyte signaling pathways in T2DM, including the PI3K/Akt cascade [210]