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Limitations There are a number of important limitations to this study, which the authors themselves acknowledge: The first is that all analyses relied on observational data, which makes strong causal inference impossible

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But they simultaneously increase the amount of harmful chemicals in tobacco smoke, as well as the potential of smoking," says Andrew Seidenberg, from Public Health at the University of North Carolina

Society for Research on Nicotine and Tobacco 27th Annual Meeting, February 24, 2021

Dual users showed a further reduction (mean difference 3.7 ( 4.2 to 3.2) mg/dL), which was comparable to that of exclusive cigarette smokers versus never smokers (mean difference 4.3 ( 4.7 to 3.9) mg/dL)

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