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The Effects of 4-OXO-DHA on Molecular Targets that can account for Cell Growth Inhibition Since 4-OXO-DHA is now unequivocally identified in plasma of rats fed DHA and it is the most potent metabolite to inhibit cell growth 12 and has a unique structural characteristics of inhibition of NF-B, further studies were performed to more widely explore the magnitude of its effects on different molecular targets using three different molecular subtypes of human breast csancer cell lines (Table 2)

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13,312 Regulation of autophagy may help remove harmful proteins and other cellular debris accumulated under inflammatory conditions, which is potentially important for maintaining the health of joint tissues

The steric mismatch induced by the Nm group compromises the correct stereochemistry required for the activation of the EF-Tu GTPase

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