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Across the cagrilintide clinical program, the dominant tolerability issues have been gastrointestinal: nausea, reduced appetite, constipation, and, less commonly, vomiting a profile shared with pramlintide and with GLP-1 agonists, and mechanistically expected from a compound that slows the stomach and engages the area postrema

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Huang et al., 2015) was successfully applied to the other tissues healing (and thereby avoiding all shortages related to the peptide + carrier complex(es) (standard angiogenic growth factors application with diverse carriers)) (see Practical Application as Support )

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